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LONG-TERM PROGNOSIS FOR THOSE WITH CHRONIC HEPATITIS B AND D
Compared with people who have chronic hepatitis B alone, those with chronic infections of both HBV and HDV are more likely to have a poor outcome. These people tend to develop cirrhosis more frequently and more rapidly than those with chronic hepatitis B alone. Approximately 60 to 70 percent ot all people with chronic hepatitis D develop cirrhosis, and 15 percent of them develop cirrhosis in two years or less from the time of initial infection. This is much more frequent and rapid than for any other form of chronic viral hepatitis. People with both chronic hepatitis B and chronic hepatitis D are also more likely to develop complications, such as liver failure and liver cancer, and are more likely to require a liver transplant as compared with people suffering from other forms of chronic viral hepatitis.
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WHAT IS HEPATITIS C?
Hepatitis C is inflammation of the liver due to a virus called the hepatitis C virus (HCV). After the discovery of the hepatitis A virus in 1973 and the hepatitis B virus in 1963, the remaining hepatitis viruses were lumped into the category of non-A non-B (NANB) hepatitis. Any cases of acute or chronic hepatitis or cirrhosis without identifiable causes were suspected to be a result of the NANB hepatitis viruses. In 1989, a major breakthrough regarding this mysterious and intriguing disease occurred—the hepatitis C virus was identified. Now, HCV is believed to be the virus responsible for more than 90 percent of all cases of NANB hepatitis.
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HCV is the most common cause of cirrhosis and liver cancer in the United States. More than 4 million Americans (approximately 2 percent of the United States population) and more than 170 million people worldwide (approximately 3 percent of the world’s population) are infected with HCV. (HCV is more prevalent in Africa, the eastern Mediterranean, Southeast Asia, and the western Pacific than in the United States.) The Centers for Disease Control (CDC) estimates that only a small percentage (probably around 5 percent) of infected individuals are even aware that they harbor this virus in their bodies.
People between the ages of forty and fifty-nine are most likely to be diagnosed with HCV. And it is estimated that there will be a fourfold increase in the number of adults diagnosed with HCV by the year 2015. While HCV can infect anyone with risk factors, it has been found to be more common among certain subgroups of people. For example, the prevalence of HCV among prison inmates is between 39 and 54 percent, among intravenous drug users between 70 and 90 percent, and among those attending Veterans Administration outpatient clinics between 18 and 40 percent.
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